Today I want to talk about polymer-drug conjugates. What’s the idea behind such conjugates? What are the advantages and challenges? And are there any polymer-drug conjugates in clinical use?
I became interested in this topic during my PhD, as I was developing a polymer carrier material for ocular use. Since my carrier should be water-soluble, conjugation was the best way to incorporate drugs into the formulation. The concept of polymer-drug conjugates had already been described in the 1970s,[1] but hadn’t really been pursued in ocular drug delivery. Here, I will highlight some advantages of this technology and if you are interested to learn more, you can read my PhD thesis here.
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